In some areas, like the lips, the numbing action can be felt much faster because the nerve receptors are located very superficially. In addition, the product needs some time to penetrate to where the pain receptors are located, deep into the dermis. These are substances that temporarily and reversibly increase the permeability of the stratum corneum - the skin barrier. TOPICAINE® is formulated to overcome this barrier, because it contains skin permeation enhancers. However, most other areas of the body take more time, because the skin elsewhere is thicker, with many keratinized layers that act as a barrier. Try it yourself, once you get the product, and you will believe it! That is because the skin there is very permeable. For example, if you put some of the gel on your lips (the red part), you will feel numb - really numb - in less than ten minutes. That said, some areas of the body numb faster than others. Please don't fall for other products that promise "instant numbing", it is just not true. Give the product time to penetrate the skin, that way you obtain the most benefit from it. HOW FAST IS THE SKIN NUMBING ACTION?Įxcellent skin numbing results are obtained 30 minutes to 1 hour post application. The explanation for this is that TOPICAINE® is formulated in a penetrating vehicle, with skin permeation enhancers that facilitate the delivery of lidocaine to where it needs to act. Independent clinical studies found it that TOPICAINE® (with lidocaine 4% ) reduces pain better than LMX-5 (with lidocaine 5%) and prescription cream EMLA (which has a combination of 2.5% lidocaine and 2.5% prilocaine). TOPICAINE®'s numbs the skin with rapid onset and proven efficacy. You won't be cancelling your next appointment because of the dreadful pain. The effective skin numbing action of TOPICAINE® allows you to concentrate on getting results, not on enduring pain. TOPICAINE® showed the highest level of anesthetic efficacy overall. This was and independent clinical study conducted at the Department of Dermatology of New Your University. "TOPICAINE® demonstrated a very rapid onset with a long duration of cutaneous anesthesia in a prospective, randomized, double-blind, controlled study investigating the efficacy of EMLA®, LMX-5® and TOPICAINE® using a 30-minute application time." TOPICAINE® 5 has lidocaine 5% in a gel with label indication: for anorectal pain. Check with your physician or nurse practitioner to see if TOPICAINE® use is appropriate for your particular case and application. Physicians and esthetic professionals use this skin numbing gel for a number of medical and beauty treatments (these are off-label uses). TOPICAINE® is indicated for the prevention and relief of pain caused by: It is a skin numbing agent with lidocaine as its active ingredient. It is a TOPICAL ANESTHETIC specially formulated to penetrate intact skin, for the relief of pain. This is the maximum concentration allowed by FDA for an over-the-counter (non-prescription required) skin numbing agent. TOPICAINE® is a non-oily, translucent gel containing lidocaine 4% in a microemulsion with skin permeation enhancers and soothing agents.Īlso available in a 5% lidocaine concentration, TOPICAINE® 5, also a gel. TOPICAINE® topical anesthetic gel is guaranteed to numb your skin and increase your comfort. On your next cosmetic medical or beauty appointment, take a vacation from pain! If you aren’t absolutely satisfied, return your product within 90 days for a prompt and courteous refund.
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